Coulbourn Instruments

Coulbourn Instruments has been providing quality behavioral and physiological research instrumentation to leading scientists worldwide for 40 years. Complete hardware/software integrated systems for in vivo studies in toxicology, pharmacology, and neuroscience for learning and memory, activity, anxiety, addiction, metabolism, contextual fear, acoustic startle, circadian rhythms, drug screening and more. Our team of behavioral application specialists is eager to assist you in finding the right configuration to meet your research goals.


Habitest Modular System: A modular animal behaviour system comprised of arenas (cages or working areas) which accept slide-in stimulus presentation modules, response sensing modules and accessories.

Arenas include two modular operant test cages.
The shuttle cage – a large one for rats, pigeons and other similar sized animals and a smaller one for mice, gerbils etc. – suitable for operant studies, feeding, drinking and other tests.
The Passive Avoidance cage – large and small – for use in active and passive avoidance studies as well as place-preference and other applications.

Slide-in stimulus-response modules include auditory and visual stimuli, liquid, pellet and dry-bulk feeders, levers, nose poke sensors, an activity monitor and dozens of other devices. Hubs may be also used a multi-bay test cages to hold more stimulus-response modules than the cages.


Graphic State 4 is a program designed to allow experimenters to create interactive experiment-control protocols for behavioral experiments using state logic. It is a conceptual extension and major improvement of state notation languages of the past. If you have used other state notation software before, you will move easily into using the Graphic State program. You’ll find a new elegance in state notation with robust power and incredible simplicity.

Graphic State uses a „point and click“ screen that presents options to be selected by the user and represents the structure of each state graphically. It is inherently user friendly because the screen contains all of the options and acts as a universal prompt. You need not learn a language or remember what to type or how to type it for each option. It is all contained in each window.

Graphic State 4 experiments or protocols are created in windows that lead the user through constructing states. This is done graphically by specifying stimuli, the elapsed-time and the input-event (response) variables necessary to exit each state and make a transition to the next.

Graphic State 4 will run on Windows Xp or Windows 7, both 32- and 64-bit, operating systems.  A single USB port is all that is needed to interface as many as 16 completely independent stations.  Update your Graphic State 2 or Graphic State 3 systems by simply adding the software upgrade and the USB interface.  All of your other hardware, Habitest Lincs, Environment Control Boards (ECB), Powerbase and of course the Habitest Environments with a wide variety of stimulus and response devices as well as various cages, runways, arenas, etc., are all compatible with Graphic State 4.

Graphic State 4 moves out of the database and includes two programs, one to build protocols and view/analyze data and another, Graphic State Run-Time, for running experiments.  Install Graphic State 4 on as many computers as you like for creating protocols and analyzing data.

protocol builder 1 protocol builder 2 protocol builder 3


TRU SCAN is a versatile and simple system to monitor open field activity.  Utilizing Coulbourn’s interchangeable sensor rings, TRU SCAN ensures precise tracking in up to three planes.  Nose poke task, place preference, conditioned freezing, light/dark tests can also be performed in our TRU SCAN test arenas.  Additional accessories, such as shock floors, video mounted TV cameras, hi-brite cue, noise/tone generators and wall mounting brackets are available for use with this system, making TRU SCAN extremely functional and flexible.

Experimental protocols are setup through a simple point-and-click user interface, filed away and recalled by number for future use.  All selected data is compiled and analyzed according to the parameters defined in the protocol.